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The Golden LEAF Biomanufacturing Training and Education Center (BTEC) is a multidisciplinary instructional center at North Carolina State University that provides education and training to develop skilled professionals for the biomanufacturing industry. Biomanufacturing refers to the use of living organisms or other biological material to produce commercially viable products. Examples include therapeutic proteins, monoclonal antibodies, and vaccines for medical use; amino acids and enzymes for food manufacturing; and biofuels and biochemicals for industrial applications. BTEC provides hands-on education and training in bioprocessing concepts and biomanufacturing methods that comply with cGMP (current Good Manufacturing Practice), a set regulations published by the United States Food and Drug Administration (FDA). BTEC reports administratively through the university's College of Engineering and is guided by an advisory board made up of representatives from the biomanufacturing industry and other organizations interested in biotechnology and biomanufacturing. In 2003, North Carolina's Golden LEAF Foundation provided almost $39 million to build BTEC, as part of a larger grant to establish a statewide public-private partnership now called NCBioImpact.〔(【引用サイトリンク】title=2003 Annual Report for the North Carolina Biotechnology Center )〕〔(【引用サイトリンク】title=WRALtechwire article )〕 The state of North Carolina provided funds for process equipment and supports the operation of the facility. The NCBioImpact partnership now includes BTEC, BRITE (Biomanufacturing Research Institute and Technology Enterprise) at North Carolina Central University, North Carolina BioNetwork of the North Carolina Community College System, NCBIO (North Carolina Biosciences Organization), the North Carolina Biotechnology Center, and the Golden LEAF Foundation. It was created to provide workforce training and development for the biotechnology industry, thereby fostering the growth of this economic sector in the state. According to the North Carolina Biotechnology Center, North Carolina is home to 528 biotechnology companies that provide 57,000 jobs and $1.92 billion in taxes for state and local government. Employment in the industry has grown 4.1% from 2008 to 2010, when other industries shed thousands of jobs. In recent years some of the world's largest pharmaceutical companies, e.g. Novartis and Merck, have located and/or expanded manufacturing operations in North Carolina.〔(【引用サイトリンク】title=Novartis Plans to Produce Vaccines by 2011 )〕〔(【引用サイトリンク】title=Merck Expansion Adds to Vaccine Core )〕 ==Facilities and equipment== BTEC opened in fall 2007 and was the first facility dedicated to biomanufacturing training.〔(【引用サイトリンク】title=2007 Annual Report for the North Carolina Biotechnology Center )〕 BTEC is 82,500 gross square feet and contains 63,000-gross square feet of laboratories, which range from small or bench scale to large-scale suites that simulate a biomanufacturing pilot plant capable of producing biopharmaceutical products. Upstream processes utilize bacteria, yeast, animal cells, and insect cells. Equipment in these spaces includes the following: * Bioreactors, glass and stainless steel (2L - 300L) and disposable (10L - 250L) * Automation systems with distributed control architecture * Downstream recovery and purification equipment, and * Analytical instrumentation The main BTEC facility is home to the North Carolina Community College System's BioNetwork Capstone Center, which operates an aseptic processing/filling suite and several bench-scale labs.〔(【引用サイトリンク】title=Capstone Center )〕 In 2012, BTEC completed construction of additional laboratories in a nearby facility for cell culture, purification, and processing of active virus. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Golden LEAF Biomanufacturing Training and Education Center」の詳細全文を読む スポンサード リンク
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